GLPG-0492 – (1215085-92-9)

GLPG-0492 is a non-steroidal selective androgen receptor modulator (SARM). It has been investigated for its potential in treating musculo-skeletal diseases such as sarcopenia, cachexia, and Duchenne muscular dystrophy (DMD).

Pre-clinical studies in the exercised mdx mouse model of DMD demonstrated that GLPG-0492 improves muscle strength, reduces fatigue, and decreases fibrosis markers, particularly in the diaphragm.

GLPG-0492 is currently in the investigational stage, with clinical trials exploring its safety and efficacy in healthy volunteers and potential therapeutic applications.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

GLPG-0492 is a non-steroidal selective androgen receptor modulator (SARM). It has been investigated for its potential in treating musculo-skeletal diseases such as sarcopenia, cachexia, and Duchenne muscular dystrophy (DMD).

Pre-clinical studies in the exercised mdx mouse model of DMD demonstrated that GLPG-0492 improves muscle strength, reduces fatigue, and decreases fibrosis markers, particularly in the diaphragm.

GLPG-0492 is currently in the investigational stage, with clinical trials exploring its safety and efficacy in healthy volunteers and potential therapeutic applications.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/GLPG-0492
https://www.medchemexpress.com/GLPG0492.html
https://www.medkoo.com/products/12821
https://go.drugbank.com/drugs/DB12461
https://www.sciencedirect.com/science/article/abs/pii/S1043661813000522

Other Names	GLPG0492, GLPG 0492, 8O59X1ACZT
IUPAC Name	4-[(4S)-4-(hydroxymethyl)-3-methyl-2, 5-dioxo-4-phenylimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
CAS	1215085-92-9
Molecular Weight	389.3
Molecular Formula	C19H14F3N3O3
SMILES	CN1C(=O)N(C(=O)[C@@]1(CO)C2=CC=CC=C2)C3=CC(=C(C=C3)C#N)C(F)(F)F

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GLPG-0492 – (1215085-92-9)

GLPG-0492 is a non-steroidal selective androgen receptor modulator (SARM). It has been investigated for its potential in treating musculo-skeletal diseases such as sarcopenia, cachexia, and Duchenne muscular dystrophy (DMD).

Pre-clinical studies in the exercised mdx mouse model of DMD demonstrated that GLPG-0492 improves muscle strength, reduces fatigue, and decreases fibrosis markers, particularly in the diaphragm.

GLPG-0492 is currently in the investigational stage, with clinical trials exploring its safety and efficacy in healthy volunteers and potential therapeutic applications.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/GLPG-0492
https://www.medchemexpress.com/GLPG0492.html
https://www.medkoo.com/products/12821
https://go.drugbank.com/drugs/DB12461
https://www.sciencedirect.com/science/article/abs/pii/S1043661813000522

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GLPG-0492 – (1215085-92-9)

GLPG-0492 is a non-steroidal selective androgen receptor modulator (SARM). It has been investigated for its potential in treating musculo-skeletal diseases such as sarcopenia, cachexia, and Duchenne muscular dystrophy (DMD).

Pre-clinical studies in the exercised mdx mouse model of DMD demonstrated that GLPG-0492 improves muscle strength, reduces fatigue, and decreases fibrosis markers, particularly in the diaphragm.

GLPG-0492 is currently in the investigational stage, with clinical trials exploring its safety and efficacy in healthy volunteers and potential therapeutic applications.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/GLPG-0492 https://www.medchemexpress.com/GLPG0492.html https://www.medkoo.com/products/12821 https://go.drugbank.com/drugs/DB12461 https://www.sciencedirect.com/science/article/abs/pii/S1043661813000522

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https://en.wikipedia.org/wiki/GLPG-0492
https://www.medchemexpress.com/GLPG0492.html
https://www.medkoo.com/products/12821
https://go.drugbank.com/drugs/DB12461
https://www.sciencedirect.com/science/article/abs/pii/S1043661813000522