L-687,384 – (95417-67-7)

L-687,384 is a potent and selective sigma receptor agonist, specifically targeting the σ1 subtype, and also exhibits properties as an NMDA antagonist. This compound has garnered significant attention in the field of medicinal chemistry due to its potential therapeutic applications.

L-687,384 has been investigated for its inhibitory effects on the Schistosoma mansoni larvae and its ability to counteract morphine-induced cAMP overdose, further highlighting its versatility in drug development.

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Sources:

https://en.wikipedia.org/wiki/L-687,384
https://pubchem.ncbi.nlm.nih.gov/compound/125328
https://www.medchemexpress.com/l-687384.html
https://www.medkoo.com/products/20977
https://www.researchgate.net/publication/273294317_Synthesis_of_benzo-fused_spiropiperidines_through_a_regioselective_free_radical-mediated_cyclization_as_key_step_a_suitable_alternative_towards_the_lead_s-1_receptor_ligand_L-687384