Tadalafil is a molecule primarily used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension (PAH). It belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors, which work by increasing blood flow to specific areas of the body. Tadalafil’s mechanism of action involves the inhibition of PDE5, an enzyme that breaks down cyclic guanosine monophosphate (cGMP), a substance that promotes smooth muscle relaxation and increased blood flow. By blocking PDE5, tadalafil enhances the effects of nitric oxide, a natural chemical produced in response to sexual stimulation, leading to improved erectile function.
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| Other Names | Cialis |
|---|---|
| IUPAC Name | (2R, 8R)-2-(1, 3-benzodioxol-5-yl)-6-methyl-3, 6, 17-triazatetracyclo[8.7.0.03, 8.011, 16]heptadeca-1(10), 11, 13, 15-tetraene-4, 7-dione |
| CAS | 171596-29-5 |
| Molecular Weight | 389.4 |
| Molecular Formula | C22H19N3O4 |
| SMILES | CN1CC(=O)N2[C@@H](C1=O)CC3=C([C@H]2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36 |