O-304 is a first-in-class, orally available pan-AMPK activator, which increases AMPK activity by suppressing the dephosphorylation of pAMPK. O-304 exhibits a great potential as a agent to treat type 2 diabetes (T2D) and associated cardiovascular complications.
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O-304 – (1261289-04-6)
O-304 is a first-in-class, orally available pan-AMPK activator, which increases AMPK activity by suppressing the dephosphorylation of pAMPK. O-304 exhibits a great potential as a agent to treat type 2 diabetes (T2D) and associated cardiovascular complications.
| Other Names | 1261289-04-6, O-304, 4-chloro-N-(2-(4-chlorobenzyl)-3-oxo-2, 3-dihydro-1, 2, 4-thiadiazol-5-yl)benzamide, O304, 4-chloro-N-[2-[(4-chlorophenyl)methyl]-3-oxo-1, 2, 4-thiadiazol-5-yl]benzamide, 4-chloro-N-{2-[(4-chlorophenyl)methyl]-3-oxo-1, 2, 4-thiadiazol-5-yl}benzamide, MFCD31657425, C16H11Cl2N3O2S, SCHEMBL1050337, SCHEMBL25745546, BCP29039, EX-A1990, AKOS037648610, AC-35558, BS-14854, HY-112233, CS-0044210, O 304, O304?, S0795, D81154 |
|---|---|
| IUPAC Name | 4-chloro-N-[2-[(4-chlorophenyl)methyl]-3-oxo-1, 2, 4-thiadiazol-5-yl]benzamide |
| CAS | 1261289-04-6 |
| Molecular Weight | 380.2 |
| Molecular Formula | C16H11Cl2N3O2S |
| SMILES | C1=CC(=CC=C1CN2C(=O)N=C(S2)NC(=O)C3=CC=C(C=C3)Cl)Cl |
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