4-Fluorophenibut – (52237-19-1)

4-Fluorophenibut is a GABAB receptor agonist that was never marketed. It is selective for the GABAB receptor over the GABAA receptor (IC50 = 1.70 μM and > 100 μM, respectively).

The drug is a GABA analogue and is closely related to baclofen (β-(4-chlorophenyl)-GABA), tolibut (β-(4-methylphenyl)-GABA), and phenibut (β-phenyl-GABA).

It is less potent as a GABAB receptor agonist than baclofen but more potent than phenibut. The substance is sometimes referred to as 4F-phenibut, F-phenibut, or baflofen and colloquially as fluorobut.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/4-Fluorophenibut
https://psychonautwiki.org/wiki/F-Phenibut
https://www.medkoo.com/products/9306
https://pubmed.ncbi.nlm.nih.gov/32735986/