Alogabat – (2230009-48-8)

Alogabat (developmental code names RG-7816 and RO7017773) is an α5 subunit-containing GABAA receptor positive allosteric modulator under development for the treatment of pervasive developmental disorders (e.g., autism) and Angelman syndrome.

It is administered orally and is currently in phase 2 clinical trials as of June 2024. Alogabat is being developed by Roche.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Alogabat (developmental code names RG-7816 and RO7017773) is an α5 subunit-containing GABAA receptor positive allosteric modulator under development for the treatment of pervasive developmental disorders (e.g., autism) and Angelman syndrome.

It is administered orally and is currently in phase 2 clinical trials as of June 2024. Alogabat is being developed by Roche.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.
Sources:
https://en.wikipedia.org/wiki/Alogabat
https://pubchem.ncbi.nlm.nih.gov/compound/134588268
https://www.medchemexpress.com/alogabat.html
https://www.medkoo.com/products/48378
https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=21578&isClinicalTrial=True
Other Names

Alogabat, Alogabat [INN], 0HPA4GK3UH, Alogabat [USAN]

IUPAC Name

6-[[5-methyl-3-(6-methylpyridin-3-yl)-1, 2-oxazol-4-yl]methoxy]-N-(oxan-4-yl)pyridazine-3-carboxamide

CAS

2230009-48-8

Molecular Weight

409.4

Molecular Formula

C21H23N5O4

SMILES

CC1=NC=C(C=C1)C2=NOC(=C2COC3=NN=C(C=C3)C(=O)NC4CCOCC4)C

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