Alogabat (developmental code names RG-7816 and RO7017773) is an α5 subunit-containing GABAA receptor positive allosteric modulator under development for the treatment of pervasive developmental disorders (e.g., autism) and Angelman syndrome.
It is administered orally and is currently in phase 2 clinical trials as of June 2024. Alogabat is being developed by Roche.
The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.
| Other Names | Alogabat, Alogabat [INN], 0HPA4GK3UH, Alogabat [USAN] |
|---|---|
| IUPAC Name | 6-[[5-methyl-3-(6-methylpyridin-3-yl)-1, 2-oxazol-4-yl]methoxy]-N-(oxan-4-yl)pyridazine-3-carboxamide |
| CAS | 2230009-48-8 |
| Molecular Weight | 409.4 |
| Molecular Formula | C21H23N5O4 |
| SMILES | CC1=NC=C(C=C1)C2=NOC(=C2COC3=NN=C(C=C3)C(=O)NC4CCOCC4)C |