Alpha GPC – (28319-77-9)

L-α-Glycerophosphorylcholine (alpha-GPC) is a natural choline compound found in the brain and a parasympathomimetic acetylcholine precursor.

It has been investigated for its potential in treating Alzheimer’s disease and other dementias. Alpha-GPC rapidly delivers choline to the brain across the blood-brain barrier and serves as a biosynthetic precursor of acetylcholine.

Industrially, alpha-GPC is produced by the chemical or enzymatic deacylation of phosphatidylcholine-enriched soy phospholipids, followed by chromatographic purification. It may also be derived from highly purified soy or sunflower lecithin.

However, alpha-GPC metabolizes to trimethylamine n-oxide in the gastrointestinal tract, which has implications for cardiovascular health, with studies indicating a 40% increased risk of stroke over ten years in users.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/Glycerophosphorylcholine
https://pubchem.ncbi.nlm.nih.gov/compound/657272#section=CAS
https://www.medchemexpress.com/sn-Glycero-3-phosphocholine.html
https://www.medkoo.com/products/11178
https://psychonautwiki.org/wiki/Alpha-GPC