Benocyclidine – (112726-66-6)

Benocyclidine, also known as BTCP, is a psychoactive molecule of the arylcyclohexylamine class, related to phencyclidine (PCP). It acts as a potent and selective dopamine reuptake inhibitor (DRI) and psychostimulant.

Unlike related compounds like PCP and ketamine, benocyclidine is a pure DRI with negligible affinity for the NMDA receptor, lacking anticonvulsant, anesthetic, hallucinogenic, or dissociative effects.

It has been used to label the dopamine transporter and was studied to identify a pharmacophore for DRI-type stimulants.

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Sources:

https://en.wikipedia.org/wiki/Benocyclidine
https://pubchem.ncbi.nlm.nih.gov/compound/123692
https://comptox.epa.gov/dashboard/chemical/details/DTXSID0042581
https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cmdc.202300048