DHEA – (53-43-0)

Dehydroepiandrosterone (DHEA) is an endogenous steroid hormone precursor and one of the most abundant circulating steroids in humans.

It is produced in the adrenal glands, gonads, and brain. DHEA serves as a metabolic intermediate in the biosynthesis of androgen and estrogen sex steroids in various tissues. It also acts as a neurosteroid, modulating neurotrophic factor receptors and binding to nuclear and cell surface receptors.

DHEA levels peak around age 20 and decline with age, potentially influencing age-related conditions. It is also studied for its effects on neurotransmitter receptors and neurotrophin receptors, with implications for neurodegenerative diseases.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Dehydroepiandrosterone (DHEA) is an endogenous steroid hormone precursor and one of the most abundant circulating steroids in humans.

It is produced in the adrenal glands, gonads, and brain. DHEA serves as a metabolic intermediate in the biosynthesis of androgen and estrogen sex steroids in various tissues. It also acts as a neurosteroid, modulating neurotrophic factor receptors and binding to nuclear and cell surface receptors.

DHEA levels peak around age 20 and decline with age, potentially influencing age-related conditions. It is also studied for its effects on neurotransmitter receptors and neurotrophin receptors, with implications for neurodegenerative diseases.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.
Sources:
https://en.wikipedia.org/wiki/Dehydroepiandrosterone
https://www.medchemexpress.com/DHEA.html
https://www.medkoo.com/products/10920
https://psychonautwiki.org/wiki/Talk:DHEA
https://pubmed.ncbi.nlm.nih.gov/9876338/
Other Names

Dehydroepiandrosterone, PRASTERONE, Dehydroisoandrosterone

IUPAC Name

(3S, 8R, 9S, 10R, 13S, 14S)-3-hydroxy-10, 13-dimethyl-1, 2, 3, 4, 7, 8, 9, 11, 12, 14, 15, 16-dodecahydrocyclopenta[a]phenanthren-17-one

CAS

53-43-0

Molecular Weight

288.4

Molecular Formula

C19H28O2

SMILES

C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC=C4[C@@]3(CC[C@@H](C4)O)C

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