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Ipamorelin – (170851-70-4)
Ipamorelin - (170851-70-4)

Ipamorelin – (170851-70-4)

Ipamorelin is a synthetic peptide and selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS). It is a pentapeptide with the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2, derived from GHRP-1.

Ipamorelin significantly increases plasma growth hormone (GH) levels in both animals and humans without affecting other hormones like prolactin, FSH, LH, or TSH. Unlike some other growth hormone secretagogues, it does not stimulate ACTH or cortisol secretion, making it highly selective for GH release.

Originally developed by Novo Nordisk, it was investigated for postoperative ileus but discontinued due to lack of efficacy.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

SKU: 170851-70-4
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Ipamorelin is a synthetic peptide and selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS). It is a pentapeptide with the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2, derived from GHRP-1.

Ipamorelin significantly increases plasma growth hormone (GH) levels in both animals and humans without affecting other hormones like prolactin, FSH, LH, or TSH. Unlike some other growth hormone secretagogues, it does not stimulate ACTH or cortisol secretion, making it highly selective for GH release.

Originally developed by Novo Nordisk, it was investigated for postoperative ileus but discontinued due to lack of efficacy.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.
Sources:
https://en.wikipedia.org/wiki/Ipamorelin
https://www.medkoo.com/products/11577
https://www.cancer.gov/publications/dictionaries/cancer-drug/def/ipamorelin
https://www.sciencedirect.com/science/article/abs/pii/S1096637499999987
Other Names

Ipamorelin [INN], IPAMORELIN ACETATE, NNC-26-0161

IUPAC Name

(2S)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide

CAS

170851-70-4

Molecular Weight

711.9

Molecular Formula

C38H49N9O5

SMILES

CC(C)(C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@H](CC2=CC3=CC=CC=C3C=C2)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)N[C@@H](CCCCN)C(=O)N)N

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