Nootkatone – (4674-50-4)

Nootkatone is a sesquiterpenoid ketone renowned for its potent grapefruit aroma and diverse bioactivities. It is primarily found in grapefruit and is valued for its antioxidant and anti-inflammatory properties. Nootkatone has demonstrated effectiveness as a neuroprotective agent, improving cognitive impairment in mouse models of Alzheimer’s disease. It is also a promising natural insecticide and repellent, effective against ticks, mosquitoes, and other pests, with a low environmental impact due to its volatile nature.

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Sources:

https://en.wikipedia.org/wiki/Nootkatone
https://pubchem.ncbi.nlm.nih.gov/compound/1268142
https://www.medchemexpress.com/nootkatone.html
https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/nootkatone
https://pubmed.ncbi.nlm.nih.gov/25326849/