Proinsulin C-Peptide (55-89) - (11097-48-6)

Proinsulin C-Peptide (55-89) – (11097-48-6)

Proinsulin C-peptide (55-89), human is a 35-amino-acid peptide fragment derived from the cleavage of proinsulin, a precursor molecule in insulin synthesis. This peptide plays a crucial role in the efficient assembly, folding, and processing of insulin within the endoplasmic reticulum of pancreatic beta cells. It is stored and secreted in equimolar amounts with insulin, making it a valuable marker for assessing endogenous insulin production.

This peptide is part of a broader category of peptides and derivatives used in metabolic disease research, particularly in the study of diabetes and its complications. Its role in cellular signaling and potential therapeutic applications make it a subject of interest in ongoing research efforts.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

SKU: 11097-48-6

Categories: Biochemical, Biological peptide

Tags: Anti-inflammatory agent, Diabetic complication therapeutic, Neuroprotective agent, Signaling molecule

Description
Additional information

Proinsulin C-peptide (55-89), human is a 35-amino-acid peptide fragment derived from the cleavage of proinsulin, a precursor molecule in insulin synthesis. This peptide plays a crucial role in the efficient assembly, folding, and processing of insulin within the endoplasmic reticulum of pancreatic beta cells. It is stored and secreted in equimolar amounts with insulin, making it a valuable marker for assessing endogenous insulin production.

This peptide is part of a broader category of peptides and derivatives used in metabolic disease research, particularly in the study of diabetes and its complications. Its role in cellular signaling and potential therapeutic applications make it a subject of interest in ongoing research efforts.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/C-peptide
https://www.medchemexpress.com/proinsulin-c-peptide-55-89-human.html
https://www.eurogentec.com/en/catalog/proinsulin-c-peptide-55-89-human-05-mg~3109c5f9-1b20-4b1a-8ec7-183af7ab5783

Other Names	Proinsulin C-Peptide (55-89) human, Proinsulin C-Peptide (55-89), human, MFCD00076294, DTXSID00745469
IUPAC Name	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[2-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[2-[[2-[(2S)-2-[[2-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-6-amino-1-[[(1S)-4-carbamimidamido-1-carboxybutyl]amino]-1-oxohexan-2-yl]amino]-1, 5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1, 5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-2-oxoethyl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1, 5-dioxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1, 5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-carboxybutanoyl]amino]propanoyl]amino]-5-oxopentanoic acid
CAS	11097-48-6
Molecular Weight	3617
Molecular Formula	C153H259N49O52
SMILES	C[C@@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)CNC(=O)CNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)N

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