RU-58841 – (154992-24-2)

RU-58841 is a nonsteroidal antiandrogen (NSAA) initially developed in the 1980s by Roussel Uclaf. It has been investigated for its potential as a topical treatment for androgen-dependent conditions such as acne, pattern hair loss, and excessive hair growth. Structurally similar to the NSAA RU-58642, RU-58841 differs in its side-chain and is related to compounds like nilutamide, flutamide, bicalutamide, and enzalutamide.

RU-58841 acts as a specific androgen receptor antagonist, demonstrating a significant effect on hair regrowth. In studies, it has been shown to increase hair growth rates in balding samples grafted onto testosterone-conditioned nude mice. The compound inhibits dihydrotestosterone-induced effects, suggesting its potential in treating androgen-dependent alopecia.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/RU-58841
https://pubchem.ncbi.nlm.nih.gov/compound/132981
https://www.medchemexpress.com/RU-58841.html
https://www.medkoo.com/products/39096
https://pubmed.ncbi.nlm.nih.gov/9415227/
https://www.sciencedirect.com/science/article/abs/pii/096007609490250X