Toremifene Citrate – (89778-27-8)

Toremifene is a selective estrogen receptor modulator (SERM) primarily used in the treatment of metastatic breast cancer in postmenopausal women with estrogen receptor-positive or unknown-status tumors.

Toremifene is a mixed agonist–antagonist of the estrogen receptor, with estrogenic effects in bone, the liver, and the uterus, and antiestrogenic effects in the breasts. It is a triphenylethylene derivative and is closely related to tamoxifen. Introduced in 1997, it was the first new antiestrogen to be introduced since tamoxifen in 1978.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Toremifene is a selective estrogen receptor modulator (SERM) primarily used in the treatment of metastatic breast cancer in postmenopausal women with estrogen receptor-positive or unknown-status tumors.

Toremifene is a mixed agonist–antagonist of the estrogen receptor, with estrogenic effects in bone, the liver, and the uterus, and antiestrogenic effects in the breasts. It is a triphenylethylene derivative and is closely related to tamoxifen. Introduced in 1997, it was the first new antiestrogen to be introduced since tamoxifen in 1978.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.
Sources:
https://en.wikipedia.org/wiki/Toremifene
https://pubchem.ncbi.nlm.nih.gov/compound/3005572
https://www.medchemexpress.com/toremifene-citrate.html
https://www.medkoo.com/products/5156
https://www.mayoclinic.org/drugs-supplements/toremifene-oral-route/description/drg-20066456
https://www.sciencedirect.com/science/article/pii/S1526820913002516
Other Names

Fareston, FC 1157a

IUPAC Name

2-[4-[(Z)-4-chloro-1, 2-diphenylbut-1-enyl]phenoxy]-N, N-dimethylethanamine;2-hydroxypropane-1, 2, 3-tricarboxylic acid

CAS

89778-27-8

Molecular Weight

598.1

Molecular Formula

C32H36ClNO8

SMILES

CN(C)CCOC1=CC=C(C=C1)/C(=C(/CCCl)\C2=CC=CC=C2)/C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

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