Follistatin 315

Follistatin is a protein encoded by the FST gene in humans, primarily known for its role in binding and neutralizing members of the TGF-β superfamily, particularly activin. It is expressed in nearly all tissues of higher animals and plays a critical role in regulating cellular proliferation, differentiation, and tissue repair. Follistatin exists in three isoforms: FS-288, FS-300, and FS-315, with FS-315 being the most abundant form in blood plasma.

It is involved in various physiological processes, including muscle growth, inflammation regulation, embryo development, and fertility. Clinically, follistatin is studied for its potential in treating conditions like muscle atrophy, type 2 diabetes, and inflammatory diseases. It also has implications in polycystic ovary syndrome (PCOS) and other metabolic disorders.

Research has shown that follistatin can enhance muscle mass by inhibiting myostatin, a negative regulator of muscle growth, and has been explored in gene therapy for muscle-related diseases. Elevated follistatin levels are associated with increased risks of cardiovascular diseases, chronic kidney disease, and insulin resistance.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/Follistatin
https://www.peptidesciences.com/follistatin-315-1mg
https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/follistatin