ABBV-CLS-7262 – (2945073-88-9)

Fosigotifator is an experimental small-molecule drug developed by AbbVie, currently undergoing clinical trials to evaluate its efficacy in treating amyotrophic lateral sclerosis (ALS).

It is formulated as a monosodium phosphate salt mixed with tromethamine, known as ABBV-CLS-7262. Fosigotifator acts as a prodrug targeting the modulation of the integrated stress response (ISR) pathway.

Fosigotifator sodium tromethamine is in Phase II clinical trials and is being investigated for its potential to inhibit ISR-related diseases.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Fosigotifator is an experimental small-molecule drug developed by AbbVie, currently undergoing clinical trials to evaluate its efficacy in treating amyotrophic lateral sclerosis (ALS).

It is formulated as a monosodium phosphate salt mixed with tromethamine, known as ABBV-CLS-7262. Fosigotifator acts as a prodrug targeting the modulation of the integrated stress response (ISR) pathway.

Fosigotifator sodium tromethamine is in Phase II clinical trials and is being investigated for its potential to inhibit ISR-related diseases.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/Fosigotifator
https://pubchem.ncbi.nlm.nih.gov/compound/166177193#section=InChIKey
https://www.medchemexpress.com/abbv-cls-7262.html
https://www.medkoo.com/products/57616
https://www.calicolabs.com/press/calico-life-sciences-announces-that-fosigotifator-abbv-cls-7262-for-vanishing-white-matter-disease-has-been-selected-for-the-fda-start-pilot-program/
https://www.alzforum.org/therapeutics/fosigotifator
https://www.neurology.org/doi/10.1212/WNL.0000000000203810

Other Names	Fosigotifator sodium tromethamine, BN9FN5629V, CHEMBL5314908, EX-A7829
IUPAC Name	sodium;2-amino-2-(hydroxymethyl)propane-1, 3-diol;[(2S)-1, 4-bis[[2-(4-chloro-3-fluorophenoxy)acetyl]amino]-2-bicyclo[2.2.2]octanyl]oxymethyl hydrogen phosphate
CAS	2945073-88-9
Molecular Weight	782.5
Molecular Formula	C29H37Cl2F2N3NaO12P
SMILES	C1CC2(CCC1(C[C@@H]2OCOP(=O)(O)[O-])NC(=O)COC3=CC(=C(C=C3)Cl)F)NC(=O)COC4=CC(=C(C=C4)Cl)F.C(C(CO)(CO)N)O.[Na+]

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ABBV-CLS-7262 – (2945073-88-9)

Fosigotifator is an experimental small-molecule drug developed by AbbVie, currently undergoing clinical trials to evaluate its efficacy in treating amyotrophic lateral sclerosis (ALS).

It is formulated as a monosodium phosphate salt mixed with tromethamine, known as ABBV-CLS-7262. Fosigotifator acts as a prodrug targeting the modulation of the integrated stress response (ISR) pathway.

Fosigotifator sodium tromethamine is in Phase II clinical trials and is being investigated for its potential to inhibit ISR-related diseases.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

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ABBV-CLS-7262 – (2945073-88-9)

Fosigotifator is an experimental small-molecule drug developed by AbbVie, currently undergoing clinical trials to evaluate its efficacy in treating amyotrophic lateral sclerosis (ALS).

It is formulated as a monosodium phosphate salt mixed with tromethamine, known as ABBV-CLS-7262. Fosigotifator acts as a prodrug targeting the modulation of the integrated stress response (ISR) pathway.

Fosigotifator sodium tromethamine is in Phase II clinical trials and is being investigated for its potential to inhibit ISR-related diseases.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

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