ITPP – (623552-11-4)

myo-Inositol trispyrophosphate (ITPP) is a membrane-permeant allosteric regulator of hemoglobin that reduces its oxygen-binding affinity, increasing oxygen release from blood into tissues. ITPP has shown potential in enhancing exercise capacity in both healthy and heart failure models by improving tissue oxygenation.

It is also being investigated for its therapeutic potential in cardiovascular diseases, cancer, and other hypoxia-related conditions.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

myo-Inositol trispyrophosphate (ITPP) is a membrane-permeant allosteric regulator of hemoglobin that reduces its oxygen-binding affinity, increasing oxygen release from blood into tissues. ITPP has shown potential in enhancing exercise capacity in both healthy and heart failure models by improving tissue oxygenation.

It is also being investigated for its therapeutic potential in cardiovascular diseases, cancer, and other hypoxia-related conditions.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/Myo-inositol_trispyrophosphate
https://www.medchemexpress.com/myo-inositol-trispyrophosphate-hexasodium.html
https://www.sciencedirect.com/science/article/pii/S0753332222009337
https://www.pnas.org/doi/10.1073/pnas.0812381106

IUPAC Name	hexasodium;[oxido-[(1R, 2S, 3S, 4R, 5S, 6R)-2, 3, 4-trihydroxy-5-[hydroxy(phosphonooxy)phosphoryl]oxy-6-[oxido(phosphonatooxy)phosphoryl]oxycyclohexyl]oxyphosphoryl] phosphate
CAS	623552-11-4
Molecular Weight	791.93
Molecular Formula	C6H12Na6O24P6
SMILES	[C@H]1([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)OP(=O)([O-])OP(=O)([O-])[O-])OP(=O)([O-])OP(=O)([O-])[O-])OP(=O)(O)OP(=O)(O)O)O)O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

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ITPP – (623552-11-4)

It is also being investigated for its therapeutic potential in cardiovascular diseases, cancer, and other hypoxia-related conditions.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/Myo-inositol_trispyrophosphate
https://www.medchemexpress.com/myo-inositol-trispyrophosphate-hexasodium.html
https://www.sciencedirect.com/science/article/pii/S0753332222009337
https://www.pnas.org/doi/10.1073/pnas.0812381106

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ITPP – (623552-11-4)

It is also being investigated for its therapeutic potential in cardiovascular diseases, cancer, and other hypoxia-related conditions.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/Myo-inositol_trispyrophosphate https://www.medchemexpress.com/myo-inositol-trispyrophosphate-hexasodium.html https://www.sciencedirect.com/science/article/pii/S0753332222009337 https://www.pnas.org/doi/10.1073/pnas.0812381106

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https://en.wikipedia.org/wiki/Myo-inositol_trispyrophosphate
https://www.medchemexpress.com/myo-inositol-trispyrophosphate-hexasodium.html
https://www.sciencedirect.com/science/article/pii/S0753332222009337
https://www.pnas.org/doi/10.1073/pnas.0812381106