Melanotan II is a synthetic peptide hormone that acts as an agonist for melanocortin receptors, particularly MC1, MC3, MC4, and MC5. Originally developed as a potential tanning agent, it stimulates melanogenesis, the process responsible for skin pigmentation, leading to darker skin. Beyond its tanning effects, Melanotan II has been investigated for its potential to induce erections in men with erectile dysfunction, although its use for this purpose is not well-supported by extensive clinical evidence.
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| Other Names | Melanotan II, Melanotan-II, MT-II, Melanotan (MT)-II |
|---|---|
| IUPAC Name | (3S, 6S, 9R, 12S, 15S, 23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2, 5, 8, 11, 14, 17-hexaoxo-1, 4, 7, 10, 13, 18-hexazacyclotricosane-23-carboxamide |
| CAS | 121062-08-6 |
| Molecular Weight | 1024.2 |
| Molecular Formula | C50H69N15O9 |
| SMILES | CCCC[C@@H](C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC1=O)CC2=CN=CN2)CC3=CC=CC=C3)CCCN=C(N)N)CC4=CNC5=CC=CC=C54)C(=O)N)NC(=O)C |