Pregabalin is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder. It is classified as a gabapentinoid and acts by binding to the α2δ-1 subunit of voltage-gated calcium channels, thereby reducing the release of excitatory neurotransmitters such as glutamate, substance P, and norepinephrine. This mechanism of action is responsible for its anticonvulsant, analgesic, and anxiolytic effects.
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| Other Names | Lyrica, 3-isobutyl GABA |
|---|---|
| IUPAC Name | (3S)-3-(aminomethyl)-5-methylhexanoic acid |
| CAS | 148553-50-8 |
| Molecular Weight | 159.23 |
| Molecular Formula | C8H17NO2 |
| SMILES | CC(C)C[C@@H](CC(=O)O)CN |