SC-13504 – (3601-19-2)

Ropizine, also known as SC-13504, is a benzhydryl piperazine compound with notable anticonvulsant properties. Ropizine acts as an allosteric modifier, decreasing the dissociation rate of [3H]DM, which contributes to its anticonvulsant effects.

Research indicates that Ropizine may play a role in the proliferation of PDGFRα+ cells through the PI3K/Akt signaling pathway, particularly in the context of diabetic conditions. This suggests its potential in understanding and addressing complications related to diabetes, such as slow transit constipation.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Ropizine, also known as SC-13504, is a benzhydryl piperazine compound with notable anticonvulsant properties. Ropizine acts as an allosteric modifier, decreasing the dissociation rate of [3H]DM, which contributes to its anticonvulsant effects.

Research indicates that Ropizine may play a role in the proliferation of PDGFRα+ cells through the PI3K/Akt signaling pathway, particularly in the context of diabetic conditions. This suggests its potential in understanding and addressing complications related to diabetes, such as slow transit constipation.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/PAR-2_antibody_(SAM11)
https://pubchem.ncbi.nlm.nih.gov/compound/9568666
https://www.medchemexpress.com/ropizine.html
https://www.medkoo.com/products/26104
https://www.sciencedirect.com/science/article/abs/pii/0028390874901026
https://pmc.ncbi.nlm.nih.gov/articles/PMC8578889/

Other Names	Ropizine, Ropizina
IUPAC Name	(E)-N-(4-benzhydrylpiperazin-1-yl)-1-(6-methylpyridin-2-yl)methanimine
CAS	3601-19-2
Molecular Weight	370.5
Molecular Formula	C24H26N4
SMILES	CC1=NC(=CC=C1)/C=N/N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4