Turkesterone – (41451-87-0)

Turkesterone is a phytoecdysteroid found in various plant species, including Ajuga turkestanica, Vitex species, Triticum aestivum, and Rhaponticum acaule.

It is structurally similar to insect steroid hormones like 20-hydroxyecdysone and acts as an ecdysteroid receptor (EcR) agonist in some insect systems.

It is believed to enhance muscle growth and strength without the androgenic side effects associated with traditional steroids. Studies have shown that turkesterone can increase protein synthesis in skeletal muscle cells, improve grip strength in rats, and exhibit anti-adipogenic effects by reducing lipid accumulation in human adipocytes.

Additionally, turkesterone has been investigated for its potential therapeutic applications in managing conditions such as diabetes, stress, and inflammation. Despite its promising benefits, further research is needed to fully understand its mechanisms of action and long-term effects.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Turkesterone is a phytoecdysteroid found in various plant species, including Ajuga turkestanica, Vitex species, Triticum aestivum, and Rhaponticum acaule.

It is structurally similar to insect steroid hormones like 20-hydroxyecdysone and acts as an ecdysteroid receptor (EcR) agonist in some insect systems.

It is believed to enhance muscle growth and strength without the androgenic side effects associated with traditional steroids. Studies have shown that turkesterone can increase protein synthesis in skeletal muscle cells, improve grip strength in rats, and exhibit anti-adipogenic effects by reducing lipid accumulation in human adipocytes.

Additionally, turkesterone has been investigated for its potential therapeutic applications in managing conditions such as diabetes, stress, and inflammation. Despite its promising benefits, further research is needed to fully understand its mechanisms of action and long-term effects.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.
Sources:
https://en.wikipedia.org/wiki/Turkesterone
https://pubchem.ncbi.nlm.nih.gov/compound/14376672
https://www.medchemexpress.com/turkesterone.html
https://www.medkoo.com/products/39940
https://pmc.ncbi.nlm.nih.gov/articles/PMC11085066/
https://draxe.com/nutrition/turkesterone-supplement/
IUPAC Name

(2S, 3R, 5R, 9R, 10R, 11R, 13R, 14S, 17S)-2, 3, 11, 14-tetrahydroxy-10, 13-dimethyl-17-[(2R, 3R)-2, 3, 6-trihydroxy-6-methylheptan-2-yl]-2, 3, 4, 5, 9, 11, 12, 15, 16, 17-decahydro-1H-cyclopenta[a]phenanthren-6-one

CAS

41451-87-0

Molecular Weight

496.6

Molecular Formula

C27H44O8

SMILES

C[C@]12C[C@H]([C@H]3C(=CC(=O)[C@H]4[C@@]3(C[C@@H]([C@@H](C4)O)O)C)[C@@]1(CC[C@@H]2[C@](C)([C@@H](CCC(C)(C)O)O)O)O)O

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