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Abaloparatide – (247062-33-5)
Abaloparatide - (247062-33-5)

Abaloparatide – (247062-33-5)

Abaloparatide is a synthetic 34-amino acid peptide analog of parathyroid hormone-related protein (PTHrP).

It is used in some countries to treat osteoporosis in postmenopausal women at high risk of fracture and in men with osteoporosis who are at high risk of fracture or have failed or are intolerant to other osteoporosis therapies.

Abaloparatide works by selectively activating the parathyroid hormone 1 receptor (PTH1R), promoting bone formation and increasing bone mineral density.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

SKU: 247062-33-5
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Abaloparatide is a synthetic 34-amino acid peptide analog of parathyroid hormone-related protein (PTHrP).

It is used in some countries to treat osteoporosis in postmenopausal women at high risk of fracture and in men with osteoporosis who are at high risk of fracture or have failed or are intolerant to other osteoporosis therapies.

Abaloparatide works by selectively activating the parathyroid hormone 1 receptor (PTH1R), promoting bone formation and increasing bone mineral density.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:
https://en.wikipedia.org/wiki/Abaloparatide
https://pubchem.ncbi.nlm.nih.gov/compound/Abaloparatide#section=CAS
https://www.medchemexpress.com/abaloparatide.html
https://medlineplus.gov/druginfo/meds/a617038.html
https://www.mayoclinic.org/drugs-supplements/abaloparatide-subcutaneous-route/description/drg-20406221
https://theros.org.uk/information-and-support/osteoporosis/treatment/abaloparatide-faqs/
Other Names

Abaloparatide, Tymlos, AVK0I6HY2U, BA058

IUPAC Name

4-[[2-[[2-[[2-[[2-[[2-[[5-amino-2-[[2-[[2-[[6-amino-2-[[2-[[6-amino-2-[[2-[[2-[[2-[[2-[[5-amino-2-[[2-[[2-[[2-[[2-(2-aminopropanoylamino)-3-methylbutanoyl]amino]-3-hydroxypropanoyl]amino]-4-carboxybutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-oxopentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-carboxypropanoyl]amino]hexanoyl]amino]acetyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylpentanoyl]amino]-5-oxopentanoyl]amino]-3-carboxypropanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-[[1-[[1-[[1-[[6-amino-1-[[1-[[1-[[1-[[6-amino-1-[[1-[[1-[[1-[(1-amino-1-oxopropan-2-yl)amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-2-methyl-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid

CAS

247062-33-5

Molecular Weight

3961

Molecular Formula

C174H300N56O49

SMILES

CCC(C)C(C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C)(C)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC1=CN=CN1)C(=O)NC(C(C)O)C(=O)NC(C)C(=O)N)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)O)NC(=O)C(CC2=CN=CN2)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)N)NC(=O)C(CC3=CN=CN3)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)C)NC(=O)C(C)N

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