GNE 5729 is a brain-permeable positive allosteric modulator of NMDAR.
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| Other Names | GNE 5729, CHEMBL3938522, (1R, 2R)-2-[7-chloro-2-[[5-chloro-3-(trifluoromethyl)pyrazol-1-yl]methyl]-4-oxopyrido[1, 2-a]pyrimidin-6-yl]cyclopropane-1-carbonitrile |
|---|---|
| IUPAC Name | (1R, 2R)-2-[7-chloro-2-[[5-chloro-3-(trifluoromethyl)pyrazol-1-yl]methyl]-4-oxopyrido[1, 2-a]pyrimidin-6-yl]cyclopropane-1-carbonitrile |
| CAS | 2026635-66-3 |
| Molecular Weight | 428.2 |
| Molecular Formula | C17H10Cl2F3N5O |
| SMILES | C1[C@H]([C@@H]1C2=C(C=CC3=NC(=CC(=O)N32)CN4C(=CC(=N4)C(F)(F)F)Cl)Cl)C#N |