GSK-2881078 – (1539314-06-1)

GSK2881078 is a selective androgen receptor modulator (SARM) developed for the prevention of muscle wasting and sarcopenia in elderly individuals. It acts as a partial agonist in androgenic tissues and a complete agonist in synthetic metabolic tissues.

In clinical trials, GSK2881078 has shown to increase muscle strength and lean mass in healthy older men and women, as well as in men with chronic obstructive pulmonary disease (COPD).

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

GSK2881078 is a selective androgen receptor modulator (SARM) developed for the prevention of muscle wasting and sarcopenia in elderly individuals. It acts as a partial agonist in androgenic tissues and a complete agonist in synthetic metabolic tissues.

In clinical trials, GSK2881078 has shown to increase muscle strength and lean mass in healthy older men and women, as well as in men with chronic obstructive pulmonary disease (COPD).

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.
Sources:
https://en.wikipedia.org/wiki/GSK2881078
https://www.medchemexpress.com/GSK-2881078.html
https://www.medkoo.com/products/9810
https://pubmed.ncbi.nlm.nih.gov/29982690/
https://go.drugbank.com/drugs/DB16888/clinical_trials?conditions=DBCOND0004466&phase=2&purpose=treatment&status=completed
Other Names

GSK2881078, (R)-1-(1-(methylsulfonyl)propan-2-yl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile, 1-[(2R)-1-methylsulfonylpropan-2-yl]-4-(trifluoromethyl)indole-5-carbonitrile

IUPAC Name

1-[(2R)-1-methylsulfonylpropan-2-yl]-4-(trifluoromethyl)indole-5-carbonitrile

CAS

1539314-06-1

Molecular Weight

330.33

Molecular Formula

C14H13F3N2O2S

SMILES

C[C@H](CS(=O)(=O)C)N1C=CC2=C1C=CC(=C2C(F)(F)F)C#N

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