GSK2881078 is a selective androgen receptor modulator (SARM) developed for the prevention of muscle wasting and sarcopenia in elderly individuals. It acts as a partial agonist in androgenic tissues and a complete agonist in synthetic metabolic tissues.
In clinical trials, GSK2881078 has shown to increase muscle strength and lean mass in healthy older men and women, as well as in men with chronic obstructive pulmonary disease (COPD).
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| Other Names | GSK2881078, (R)-1-(1-(methylsulfonyl)propan-2-yl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile, 1-[(2R)-1-methylsulfonylpropan-2-yl]-4-(trifluoromethyl)indole-5-carbonitrile |
|---|---|
| IUPAC Name | 1-[(2R)-1-methylsulfonylpropan-2-yl]-4-(trifluoromethyl)indole-5-carbonitrile |
| CAS | 1539314-06-1 |
| Molecular Weight | 330.33 |
| Molecular Formula | C14H13F3N2O2S |
| SMILES | C[C@H](CS(=O)(=O)C)N1C=CC2=C1C=CC(=C2C(F)(F)F)C#N |