ITPP Hexasodium Salt – (23103-35-7)

myo-Inositol trispyrophosphate (ITPP) is a membrane-permeant allosteric regulator of hemoglobin that reduces its oxygen-binding affinity, increasing oxygen release from blood into tissues. ITPP has shown potential in enhancing exercise capacity in both healthy and heart failure models by improving tissue oxygenation.

It is also being investigated for its therapeutic potential in cardiovascular diseases, cancer, and other hypoxia-related conditions.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

myo-Inositol trispyrophosphate (ITPP) is a membrane-permeant allosteric regulator of hemoglobin that reduces its oxygen-binding affinity, increasing oxygen release from blood into tissues. ITPP has shown potential in enhancing exercise capacity in both healthy and heart failure models by improving tissue oxygenation.

It is also being investigated for its therapeutic potential in cardiovascular diseases, cancer, and other hypoxia-related conditions.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.
Sources:
https://en.wikipedia.org/wiki/Myo-inositol_trispyrophosphate
https://www.medchemexpress.com/myo-inositol-trispyrophosphate-hexasodium.html
https://www.sciencedirect.com/science/article/pii/S0753332222009337
https://www.pnas.org/doi/10.1073/pnas.0812381106
Other Names

myo-Inositol Trispyrophosphate Hexasodium Salt, myo-Inositol trispyrophosphate hexasodium

IUPAC Name

hexasodium;4, 6, 11, 13, 18, 20-hexaoxido-3, 5, 7, 10, 12, 14, 17, 19, 21-nonaoxa-4λ5, 6λ5, 11λ5, 13λ5, 18λ5, 20λ5-hexaphosphatetracyclo[14.5.0.02, 8.09, 15]henicosane 4, 6, 11, 13, 18, 20-hexaoxide

CAS

23103-35-7

Molecular Weight

737.88

Molecular Formula

C6H6Na6O21P6

SMILES

C12C(C3C(C4C1OP(=O)(OP(=O)(O4)[O-])[O-])OP(=O)(OP(=O)(O3)[O-])[O-])OP(=O)(OP(=O)(O2)[O-])[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

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