JNJ-28330835 is a selective androgen receptor modulator (SARM) that has shown potential in preclinical studies for enhancing muscle growth and sexual behavior with minimal effects on prostate size. It is an orally active compound that has demonstrated muscle selectivity in orchidectomized rat models, promoting lean body mass and reducing prostate weight.
JNJ-28330835 has also been observed to stimulate sexual behavior in female rats and reduce bone turnover. The compound is currently in the investigational stage and is being studied for its potential therapeutic applications in muscle-wasting diseases and sexual function disorders.
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| Other Names | UNII-544SF265DA, 544SF265DA |
|---|---|
| IUPAC Name | (5S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-5-methyl-3-(trifluoromethyl)-1, 4-dihydropyrazole-5-carboxamide |
| CAS | 888072-47-7 |
| Molecular Weight | 364.25 |
| Molecular Formula | C14H10F6N4O |
| SMILES | C[C@]1(CC(=NN1)C(F)(F)F)C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F |