Lanosterol is a tetracyclic triterpenoid and a key intermediate in cholesterol biosynthesis. It is the precursor to cholesterol and is naturally found in the eye lenses of vertebrates, playing a role in maintaining lens clarity. Lanosterol has been studied for its potential to inhibit the aggregation of crystallin proteins, which can lead to cataracts. Research indicates that lanosterol may have therapeutic benefits as an eye drop supplement to dissolve cataracts, although its solubility and bioavailability in the eye have posed challenges.
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| Other Names | Lanosterin, Lanster, Botalan base 138 |
|---|---|
| IUPAC Name | (3S, 5R, 10S, 13R, 14R, 17R)-4, 4, 10, 13, 14-pentamethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2, 3, 5, 6, 7, 11, 12, 15, 16, 17-decahydro-1H-cyclopenta[a]phenanthren-3-ol |
| CAS | 79-63-0 |
| Molecular Weight | 426.7 |
| Molecular Formula | C30H50O |
| SMILES | C[C@H](CCC=C(C)C)[C@H]1CC[C@@]2([C@@]1(CCC3=C2CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C |