Prolylrapamycin (21-Norrapamycin) is a derivative of Rapamycin. It exhibits antifungal activity, inhibiting Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum.
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| Other Names | 21-Norrapamycin |
|---|---|
| IUPAC Name | (1R, 8S, 11S, 14R, 15Z, 17R, 18R, 20R, 22S, 23Z, 25E, 27E, 29S, 31S, 34R)-1, 17-dihydroxy-11-[(2R)-1-[(1S, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-18, 29-dimethoxy-14, 16, 20, 22, 28, 34-hexamethyl-10, 35-dioxa-4-azatricyclo[29.3.1.04, 8]pentatriaconta-15, 23, 25, 27-tetraene-2, 3, 9, 13, 19-pentone |
| CAS | 156223-31-3 |
| Molecular Weight | 900.15 |
| Molecular Formula | C50H77NO13 |
| SMILES | C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C\[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C\[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC |