0
Home
Products
PT 141 – (1607799-13-2)
PT 141 - (1607799-13-2)

PT 141 – (1607799-13-2)

Bremelanotide is a molecule designed to treat low sexual desire in premenopausal women, specifically addressing generalized hypoactive sexual desire disorder (HSDD) without underlying medical, psychiatric, or relationship issues.

Bremelanotide is a cyclic heptapeptide lactam analogue of α-melanocyte-stimulating hormone (α-MSH) and acts as a non-selective agonist of the melanocortin receptors, primarily targeting the MC3 and MC4 receptors.

The development of bremelanotide began with studies in the 1960s that showed α-MSH induced sexual arousal in rats. By the 1980s, researchers at the University of Arizona were developing α-MSH analogs as potential sunless tanning agents, leading to the creation of melanotan-I and melanotan-II. Bremelanotide was synthesized as a metabolite of melanotan-II and was found to have a different structure, lacking the C-terminal amide group.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

SKU: 1607799-13-2
Categories: ,
Tags: , ,

Bremelanotide is a molecule designed to treat low sexual desire in premenopausal women, specifically addressing generalized hypoactive sexual desire disorder (HSDD) without underlying medical, psychiatric, or relationship issues.

Bremelanotide is a cyclic heptapeptide lactam analogue of α-melanocyte-stimulating hormone (α-MSH) and acts as a non-selective agonist of the melanocortin receptors, primarily targeting the MC3 and MC4 receptors.

The development of bremelanotide began with studies in the 1960s that showed α-MSH induced sexual arousal in rats. By the 1980s, researchers at the University of Arizona were developing α-MSH analogs as potential sunless tanning agents, leading to the creation of melanotan-I and melanotan-II. Bremelanotide was synthesized as a metabolite of melanotan-II and was found to have a different structure, lacking the C-terminal amide group.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.
Sources:
https://en.wikipedia.org/wiki/Bremelanotide
https://www.medchemexpress.com/bremelanotide.html
https://www.medkoo.com/products/23290
https://pubmed.ncbi.nlm.nih.gov/12851303/
https://www.sciencedirect.com/topics/medicine-and-dentistry/bremelanotide
Other Names

Bremelanotide Acetate, Bremelanotide (Acetate), Vyleesi, PV2WI7495P

IUPAC Name

(3S, 6S, 9R, 12S, 15S, 23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2, 5, 8, 11, 14, 17-hexaoxo-1, 4, 7, 10, 13, 18-hexazacyclotricosane-23-carboxylic acid;acetic acid

CAS

1607799-13-2

Molecular Weight

1085.2

Molecular Formula

C52H72N14O12

SMILES

CCCC[C@@H](C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC1=O)CC2=CN=CN2)CC3=CC=CC=C3)CCCN=C(N)N)CC4=CNC5=CC=CC=C54)C(=O)O)NC(=O)C.CC(=O)O

Related products

No products in the cart.