Salmon calcitonin is a peptide hormone derived from salmon, composed of 32 amino acids and exhibiting a structure distinct from human calcitonin with 13 differing amino acids. It is primarily used in medical treatments due to its potency, being twenty times more active than human calcitonin and possessing a longer half-life.
Clinically, salmon calcitonin is employed to manage conditions such as Paget’s disease, severe hypercalcemia, and gynecomastia. Its effectiveness in osteoporosis treatment is notable, with studies demonstrating its ability to reduce fracture rates in postmenopausal women by inhibiting osteoclastic bone resorption.
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| IUPAC Name | Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 |
|---|---|
| CAS | 47931-85-1 |
| Molecular Weight | 3431.85 |
| Molecular Formula | C145H240N44O48S |