Y-134 – (849662-80-2)

Y134 is a selective and orally active estrogen receptor (ER) modulator (SERM) that exhibits potent antagonist activity at both ERα and ERβ. With a 121.1-fold selectivity for ERα over ERβ, Y134 effectively inhibits estrogen-stimulated proliferation of ER-positive human breast cancer cells.

This compound demonstrates significant potential in the field of breast cancer research and treatment, particularly due to its high affinity for ERα, which is a key target in many breast cancer therapies.

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Sources:

https://pubchem.ncbi.nlm.nih.gov/compound/11784736
https://www.medchemexpress.com/y134.html
https://www.medkoo.com/products/54040
https://www.sciencedirect.com/science/article/abs/pii/S1389172303801901