Enclomiphene (Citrate) – (7599-79-3)

Enclomiphene, also known as (E)-Clomiphene or trans-Clomiphene, is a non-steroidal selective estrogen receptor modulator (SERM) that acts as an estrogen receptor antagonist. It is one of the two stereoisomers of clomiphene, with the other being zuclomiphene.

Enclomiphene primarily antagonizes estrogen receptors in the pituitary gland, reducing negative feedback by estrogen on the hypothalamic-pituitary-gonadal axis. This action increases gonadotropin secretion, leading to enhanced testosterone production in men.

Enclomiphene has been investigated for the treatment of male hypogonadism and type 2 diabetes. Unlike testosterone replacement therapy, enclomiphene stimulates endogenous testosterone production without suppressing spermatogenesis.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Enclomiphene, also known as (E)-Clomiphene or trans-Clomiphene, is a non-steroidal selective estrogen receptor modulator (SERM) that acts as an estrogen receptor antagonist. It is one of the two stereoisomers of clomiphene, with the other being zuclomiphene.

Enclomiphene primarily antagonizes estrogen receptors in the pituitary gland, reducing negative feedback by estrogen on the hypothalamic-pituitary-gonadal axis. This action increases gonadotropin secretion, leading to enhanced testosterone production in men.

Enclomiphene has been investigated for the treatment of male hypogonadism and type 2 diabetes. Unlike testosterone replacement therapy, enclomiphene stimulates endogenous testosterone production without suppressing spermatogenesis.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.
Sources:
https://en.wikipedia.org/wiki/Enclomifene
https://www.medchemexpress.com/enclomiphene.html
https://www.medkoo.com/products/45808
https://conciergemdla.com/blog/enclomiphene-therapy-science/
Other Names

trans-Clomiphene citrate, trans-Clomifene citrate, CLOMIPHENE CITRATE

IUPAC Name

2-[4-[(E)-2-chloro-1, 2-diphenylethenyl]phenoxy]-N, N-diethylethanamine;2-hydroxypropane-1, 2, 3-tricarboxylic acid

CAS

7599-79-3

Molecular Weight

598.1

Molecular Formula

C32H36ClNO8

SMILES

CCN(CC)CCOC1=CC=C(C=C1)/C(=C(\C2=CC=CC=C2)/Cl)/C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

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