Epitalon is a synthetic tetrapeptide with the amino acid sequence Ala-Glu-Asp-Gly, known for its potential anti-aging properties. It functions as a telomerase activator, promoting telomere elongation in human somatic cells, which may extend cellular lifespan.
Studies suggest Epitalon reduces chromosomal aberrations, enhances antioxidant enzyme activity, and exhibits oncostatic and anti-metastatic effects in animal models. In humans, it has shown potential to increase telomere length, restore melatonin secretion, and improve clinical outcomes in conditions like retinitis pigmentosa and pulmonary tuberculosis.
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| Other Names | Epithalon, Glycine, L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl- Ala-Glu-Asp-Gly |
|---|---|
| IUPAC Name | (4S)-4-[[(2S)-2-aminopropanoyl]amino]-5-[[(2S)-3-carboxy-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid |
| CAS | 307297-39-8 |
| Molecular Weight | 390.35 |
| Molecular Formula | C14H22N4O9 |
| SMILES | C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)O)N |