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Ghrp 6, Hexapeptide-2 – (87616-84-0)
GHRP-6 (Growth Hormone-Releasing Peptide-6) is a synthetic hexapeptide that acts as a growth hormone secretagogue. It stimulates the release of growth hormone (GH) by activating the ghrelin receptor (GHSR), also known as the growth hormone secretagogue receptor.
Unlike growth hormone-releasing hormone (GHRH), GHRP-6 does not share sequence homology and functions through a distinct receptor pathway. It is a potent GH stimulator without opioid activity.
GHRP-6 has been shown to increase GH secretion in a dose-dependent manner, with effects mediated through the phosphatidylinositol (PI) turnover pathway, involving protein kinase C (PKC) and calcium mobilization.
It also acts as a negative allosteric modulator of ghrelin signaling. GHRP-6 is used in research to study GH release mechanisms and has potential applications in metabolic and growth-related studies.
The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.
https://en.wikipedia.org/wiki/GHRP-6
| Other Names | GH-Releasing peptide, His(1)-lys(6)-ghrp |
|---|---|
| IUPAC Name | (2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide |
| CAS | 87616-84-0 |
| Molecular Weight | 873 |
| Molecular Formula | C46H56N12O6 |
| SMILES | C[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@H](CC3=CC=CC=C3)C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@@H](CC4=CNC5=CC=CC=C54)NC(=O)[C@H](CC6=CN=CN6)N |
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