MCP (Modified Citrus Pectin) – (9000-69-5)

Modified citrus pectin (MCP) is a dietary supplement derived from citrus fruits, processed to enhance its digestibility and absorption. This natural polysaccharide is primarily composed of D-polygalacturonates, which are more readily absorbed by the human digestive system compared to unmodified pectin.

MCP has gained attention for its potential health benefits, particularly in cancer treatment and prevention. Recent studies have shown that MCP can inhibit the survival and M2-like polarization of tumor-associated macrophages (TAMs) in the hypoxic microenvironment of breast cancer, thereby suppressing tumor growth and metastasis.

Additionally, in a prospective phase II study, MCP demonstrated long-term efficacy and safety in patients with non-metastatic biochemically relapsed prostate cancer, with 85% of patients showing a durable response after 18 months of treatment.

Despite these promising findings, further research is needed to fully understand the mechanisms and efficacy of MCP in various cancer types.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/Modified_citrus_pectin
https://www.medchemexpress.com/mce_publications/34462562.html
https://pubmed.ncbi.nlm.nih.gov/37630724/