Epimedium, commonly known as horny goat weed, is a genus of flowering plants in the Berberidaceae family. It is native to China and other parts of Asia, with some species found in the Mediterranean region. The plant is known for its four-parted, spider-like flowers and is used in traditional medicine for its potential aphrodisiac and medicinal properties.
The active compound, icariin, is a weak PDE5 inhibitor, which has led to its use in men’s sexual health supplements, though clinical evidence remains limited.
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| Other Names | Icariin, Ieariline, CHEBI:78420, UNII-VNM47R2QSQ |
|---|---|
| IUPAC Name | 5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S, 3R, 4S, 5S, 6R)-3, 4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S, 3R, 4R, 5R, 6S)-3, 4, 5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one |
| CAS | 489-32-7 |
| Molecular Weight | 676.7 |
| Molecular Formula | C33H40O15 |
| SMILES | C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O |