Melatonan 1 – (75921-69-6)

Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) and a potent non-selective melanocortin receptor (MCR) agonist. It is designed to stimulate melanogenesis, the process responsible for skin pigmentation, by mimicking the actions of α-MSH on melanocortin type 1 receptors (MC1R) in melanocytes. This property makes Melanotan I a subject of interest in research related to sun-induced skin cancer, melanoma, inflammation, and male erectile dysfunction.

In clinical trials, Melanotan I has demonstrated its ability to enhance tanning when combined with UV-B light or sunlight. Studies have shown that it can achieve significant tanning with reduced sun exposure, and the tan is maintained longer compared to sunlight exposure alone.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

SKU: 75921-69-6
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Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) and a potent non-selective melanocortin receptor (MCR) agonist. It is designed to stimulate melanogenesis, the process responsible for skin pigmentation, by mimicking the actions of α-MSH on melanocortin type 1 receptors (MC1R) in melanocytes. This property makes Melanotan I a subject of interest in research related to sun-induced skin cancer, melanoma, inflammation, and male erectile dysfunction.

In clinical trials, Melanotan I has demonstrated its ability to enhance tanning when combined with UV-B light or sunlight. Studies have shown that it can achieve significant tanning with reduced sun exposure, and the tan is maintained longer compared to sunlight exposure alone.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.
Sources:
https://en.wikipedia.org/wiki/Melanotan_I
https://www.medchemexpress.com/Melanotan_I.html
https://pubmed.ncbi.nlm.nih.gov/15262693/
Other Names

Melanotan I, Melanotan-1, NDP-alpha-MSH, 4-Nle-7-phe-alpha-msh

IUPAC Name

(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]-5-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid

CAS

75921-69-6

Molecular Weight

1646.8

Molecular Formula

C78H111N21O19

SMILES

CCCC[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N5CCC[C@H]5C(=O)N[C@@H](C(C)C)C(=O)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC6=CC=C(C=C6)O)NC(=O)[C@H](CO)NC(=O)C

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