Mirodenafil Dihydrochloride – (862189-96-6)

Mirodenafil is a selective phosphodiesterase 5 (PDE5) inhibitor developed by SK Chemicals Life Science. Mirodenafil’s mechanism of action involves inhibiting the PDE5 enzyme, which increases cyclic guanosine monophosphate levels, leading to smooth muscle relaxation and increased blood flow to the penis. This action is crucial for treating erectile dysfunction.

Additionally, mirodenafil has been studied for its potential in managing other conditions such as Alzheimer’s disease and systemic sclerosis. Research indicates that mirodenafil may exert neuroprotective effects by activating the cGMP/PKG/CREB signaling pathway and enhancing neuronal survival. It also shows promise in ameliorating skin fibrosis by inhibiting the TGF-β signaling pathway.

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Sources:

https://en.wikipedia.org/wiki/Mirodenafil
https://www.medchemexpress.com/Mirodenafil.html
https://www.medkoo.com/products/15858
https://www.sciencedirect.com/topics/medicine-and-dentistry/mirodenafil
https://go.drugbank.com/drugs/DB11792