Carbetocin is a synthetic peptide analog of oxytocin, used primarily to prevent excessive bleeding after childbirth, particularly following Cesarean sections.
It functions as an oxytocin receptor agonist, binding to and activating oxytocin receptors in the uterus, which induces uterine contractions and helps control postpartum hemorrhage.
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| Other Names | Carbetocin, Pabal, Carbetocino, Carbetocinum |
|---|---|
| IUPAC Name | (2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(3R, 6S, 9S, 12S, 15S)-6-(2-amino-2-oxoethyl)-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-methoxyphenyl)methyl]-5, 8, 11, 14, 17-pentaoxo-1-thia-4, 7, 10, 13, 16-pentazacycloicosane-3-carbonyl]pyrrolidine-2-carboxamide |
| CAS | 37025-55-1 |
| Molecular Weight | 988.2 |
| Molecular Formula | C45H69N11O12S |
| SMILES | CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSCCCC(=O)N[C@H](C(=O)N1)CC2=CC=C(C=C2)OC)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N |