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FGL – (499993-62-3)
FGL - (499993-62-3)

FGL – (499993-62-3)

FGL peptide is a polypeptide derived from the neural cell adhesion molecule (NCAM), specifically from the interconnecting loop region of the second fibronectin type III module. It mimics the interaction of NCAM with fibroblast growth factor receptor (FGFR), promoting neurite outgrowth, neuronal survival, and exhibiting neuroprotective effects.

FGL has been shown to reduce neuroinflammation by attenuating glial cell activation, particularly in aged brains, and has potential therapeutic applications in age-related cognitive decline and neurodegenerative diseases. It is used in research for protein interaction studies, functional analysis, and epitope screening.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

SKU: 499993-62-3
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FGL peptide is a polypeptide derived from the neural cell adhesion molecule (NCAM), specifically from the interconnecting loop region of the second fibronectin type III module. It mimics the interaction of NCAM with fibroblast growth factor receptor (FGFR), promoting neurite outgrowth, neuronal survival, and exhibiting neuroprotective effects.

FGL has been shown to reduce neuroinflammation by attenuating glial cell activation, particularly in aged brains, and has potential therapeutic applications in age-related cognitive decline and neurodegenerative diseases. It is used in research for protein interaction studies, functional analysis, and epitope screening.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.
Sources:
https://en.wikipedia.org/wiki/FGL
https://www.medchemexpress.com/fgl-peptide.html
https://pubmed.ncbi.nlm.nih.gov/23337536/
https://www.sciencedirect.com/science/article/abs/pii/S0014488611003335
Other Names

FGL peptide, HY-P3281, DA-53184, CS-0655069

IUPAC Name

(4S)-4-amino-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-5-amino-1-[[(2S)-5-amino-1-[[2-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(1S)-1-carboxyethyl]amino]-1-oxohexan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-1, 5-dioxopentan-2-yl]amino]-1, 5-dioxopentan-2-yl]amino]-1, 4-dioxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

CAS

499993-62-3

Molecular Weight

1649.8

Molecular Formula

C71H116N20O25

SMILES

C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(=O)O)N

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