J-147 – (1146963-51-0)

J147 is a potent, orally active neuroprotective agent designed for cognitive enhancement. It effectively crosses the blood-brain barrier (BBB) and inhibits monoamine oxidase B (MAO B) and the dopamine transporter. J147 has shown significant potential in addressing Alzheimer’s disease (AD) by reversing cognitive impairment in aged AD mice and providing immediate cognition benefits. It is also noted for its neurotrophic properties and safety in animal studies.

The above information is displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

J147 is a potent, orally active neuroprotective agent designed for cognitive enhancement. It effectively crosses the blood-brain barrier (BBB) and inhibits monoamine oxidase B (MAO B) and the dopamine transporter. J147 has shown significant potential in addressing Alzheimer’s disease (AD) by reversing cognitive impairment in aged AD mice and providing immediate cognition benefits. It is also noted for its neurotrophic properties and safety in animal studies.

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/Fosigotifator
https://www.medchemexpress.com/j147.html
https://www.medkoo.com/products/6843
https://www.sciencedirect.com/science/article/pii/S0753332222000361

Other Names	j147, UNII-Z41H3C5BT9, Z41H3C5BT9
IUPAC Name	N-(2, 4-dimethylphenyl)-2, 2, 2-trifluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]acetamide
CAS	1146963-51-0
Molecular Weight	350.3
Molecular Formula	C18H17F3N2O2
SMILES	CC1=CC(=C(C=C1)N(C(=O)C(F)(F)F)/N=C/C2=CC(=CC=C2)OC)C

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J-147 – (1146963-51-0)

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/Fosigotifator
https://www.medchemexpress.com/j147.html
https://www.medkoo.com/products/6843
https://www.sciencedirect.com/science/article/pii/S0753332222000361

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J-147 – (1146963-51-0)

The above informationis displayed for information purpose only, and has not been reviewed by EON nor does EON attests or validates the accuracy nor does it constitutes a recommendation or validation.

Sources:

https://en.wikipedia.org/wiki/Fosigotifator https://www.medchemexpress.com/j147.html https://www.medkoo.com/products/6843 https://www.sciencedirect.com/science/article/pii/S0753332222000361

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https://en.wikipedia.org/wiki/Fosigotifator
https://www.medchemexpress.com/j147.html
https://www.medkoo.com/products/6843
https://www.sciencedirect.com/science/article/pii/S0753332222000361