Prucalopride is a selective serotonin 5-HT4 receptor agonist used to treat chronic constipation. It enhances colonic motility by stimulating serotonin receptors in the gastrointestinal tract, promoting bowel movements.
Prucalopride’s mechanism involves high-affinity binding to 5-HT4 receptors, improving motility without significant cardiovascular risks.
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| Other Names | Resolor, Prucalopride Succinat, Prucalopride (succinate) |
|---|---|
| IUPAC Name | 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2, 3-dihydro-1-benzofuran-7-carboxamide;butanedioic acid |
| CAS | 179474-85-2 |
| Molecular Weight | 486 |
| Molecular Formula | C22H32ClN3O7 |
| SMILES | COCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl.C(CC(=O)O)C(=O)O |